Research Center for Engineering of
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Title: The antitumoral effect of locoregional magnetic cobalt ferrite in dog mammary adenocarcinoma
Published In: Journal of Magnetism and Magnetic Materials, Vol. 225, No. (1-2), pp. 235-240
Description: The endocytosis of nanosized magnetic particles by tumor cells led to numerous tests to establish the use of this phenomenon in antitumor therapy. The direct antitumor effect of a biocompatible cobalt-ferrite-based magnetic fluid directly inoculated in bitch mammary tumors was studied. A direct correlation between tumor cell lysis and cobaltferrite was established in tumors. Massive endocytosis of magnetic particles was observed 1 h after the contact of magnetic fluid with tumor cells.
ISSN:ISSN: 0304-8853
DOI:DOI: 10.1016/S0304-8853(00)01263-4
Publication year: 2000
Keywords:Antitumor effect; Cobaltferrite; Mammary tumor; Adenocarcinoma; Dog; Breast tumor; Magneticcobalt particles; Endocytosis
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Authors: SINCAI Mariana , GANGA Doina , BICA Doina , VEKAS Ladislau ,
Type: International Journal Article
Laboratory: Rheology Laboratory
Institution: ARFT