Research Center for Engineering of
                Systems with Complex Fluids
Title: Particle motion in coronary serial stenoses
Published In: WIT Transaction on Biomedicine and Health vol 17, WIT Press, 2013,
Description: Atherosclerosis creating a constriction can significantly alter the local blood flow dynamics. From a biological aspect, the changes that take place in the flow have a profound effect on the structure and function of the arterial wall and the development of the disease. The purpose of this paper was to non-invasively assess hemodynamic parameters such as wall shear stress, wall pressure and particle depositions with computational fluid dynamics (CFD) in coronary artery serial stenoses. A 3-D model of a serial stenosed RCA was reconstructed based on multislice computerized tomography images. Energy loss associated with such flow expansion after each constriction will be large and consequently the pressure drop will be higher. Pressure drop across the stenoses ST1 and ST3 is lower (4.62 mmHg and 4.81 mmHg respectively) during the time T2 = 0.79s, but is significant during the peak systole T1 = 0.26s. The maximum WSS in the proximal stenosis ST1 is about 254 Pa, and in the distal stenosis ST3 are 232 Pa. One diameter downstream of the each stenosis, the WSS is low because of the formation of the recirculation zone.
ISBN:ISSN: 1743-3525
ISSN:ISBN: 978-1-84564-706-3
DOI:DOI: 10.2495/BIO130151
Publication year: 2013
Keywords:blood flow, coronary artery diseases, hemodynamics, pressure drop, wall shear stress
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Authors: BERNAD Sandor , TOTOREAN Alin , BERNAD Elena , SUSAN-RESIGA Romeo ,
Type: International Conference Proceedings
Link: http://dx.doi.org/10.2495/BIO130151
Laboratory: Numerical Simulation and Parallel Computing Laboratory
Institution: ARFT